Leshchuk S.I., Danilovtseva E.N., Serdjuk L.V., Popkova S.M., Annenkov V.V. 2011. Method of producing erythrocytic diagnostic antigen. Patent RU 2429483.
FIELD: medicine.
SUBSTANCE: method of producing an erythrocytic diagnostic antigen is implemented by antigen erythrocyte opsonisation in the present of a conjugating agent, which is presented by poly-1-vinylimidazole or copolymer of 1-vinylimidazole and acrylic acid at the concentration 42 mole % of 1-vinylimidazole links and the concentration of an aqueous polymer solution of 0.01-0.04 mg/ml.
EFFECT: higher sensitivity of the erythrocytic diagnostic antigen and impoverishment of the conjugating agent with long shelf life of the diagnostic agent.