Annenkov V.V., Leshuk S.I., Kruglova V.A., Shmeleva E.A., Popkova S.M. 1999. Method of preparing antibodies raised to diphtheria corynebacteria Patent RU 2129014.
FIELD: medicine, immunology.
SUBSTANCE: for preparing antibodies raised to diphtheria corynebacteria method involves the use of synthetic polyelectrolytes poly-5-vinyl- -tetrazole and copolymer of 5-isopropenyltetrazole with 1-vinylpyrrolidone (2: 1) at concentration 0.4-0.6 mg/ml as immunoadjuvants. Invention can be used for preparing protective antibodies raised to bacteria in animals and for production of hyperimmune sera.
EFFECT: enhanced and prolonged effect of a preparation "Codivac".